A thienotriazolodiazepine is a heterocyclic compound containing a diazepine ring fused to thiophene and triazole rings. Thienotriazolodiazepine forms the central core of several pharmaceutical drugs including:
- α-Hydroxyetizolam
- Brotizolam
- Ciclotizolam
- Clotizolam
- Deschloroclotizolam
- Deschloroetizolam
- Etizolam
- Flubrotizolam
- Fluclotizolam
- Fluetizolam
- Metizolam
Thienotriazolodiazepines interact with the benzodiazepine receptor site, they typically have similar effects as 1,4-benzodiazepines (such as diazepam) and triazolobenzodiazepines (such as alprazolam).
Thienotriazolodiazepines that are not GABAA receptor positive allosteric modulators include:
- Apafant
- Israpafant
- JQ1
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